- Sawsan Abusharkh
Dr. rer.nat. Sawsan Abusharkh
- Biomedical Physics & Nanotechnology
- Assistant Professor in Biomedical Physics, Physiology & Pharmacology, Department, Medicine College, Al-Quds University
- Vice Dean of Scientific Research, AQU
- Groupleader of Biophysics Research Laboratory
Sawsan Abusharkh is an assistant professor of Biomedical Physics, Physiology and Pharmacology Department-Medicine College and Groupleader at the Biophysics Research Laboratory. Currently, she is a vice dean of scientific research at Al-Quds university, Palestine.
she got her Bachelor Degree in Physics as a Major and Material Engineering as a Minor at Al- Quds University on 2007. After Graduation she was hired as a researcher assistant in the Biophysics research Laboratory from 2007 to 2009 and during this time she did her Master Degree in the field of Biophysics. From 2009 to 2016,
she travelled to Germany to start her PhD in Biomedical Physics at Max-Planck Institute for Biomedicine and Bioengineering in the Technical University of Dresden, Germany. From 2016, she started her work at Al-Quds University as Assistant Professor and a Groupleader at the Biophysics Research Laboratory.
During her Ph.D. thesis, she has established state of the art spectroscopic methods that allow addressing molecular interactions between cell membrane biomolecules extracted from model microorganisms and their hydration shells by time-resolved infrared spectroscopy (ATR-FTIR spectroscopy). She has published
several peer-reviewed articles and participated in numerous international conferences, symposiums and workshops.
Her current research focuses on the design, formulation, biomedical characterization and evaluation of lipid-based Nano-Medicines to deliver different chemotherapeutic and genetic drugs to the cells. A key step in this development process is the investigation of Nano-Bio interactions at molecular and cellular level using Advanced Spectroscopic and Microscopic Techniques.
Specific methods and techniques used in her research include: preformed nanocarriers and Nanoparticles, different Drug-loading techniques, freeze-fracture, and evaluation of in vivo pharmacokinetics of fully established Drug-nanocarriers.
In September 2019, she has been rewarded Loreal UNESCO For Women In Science Fellowship for developing a novel alternative (drug-nano capsules) to chemotherapeutic approaches for cancer treatment. Currently, she has established the drug delivery research group at Al-Quds University and she is supervising 7 master students whom evaluate different targeted drug delivery mechanisms in collaboration with distinguished research institutes in this field in Germany.
Running Research Projects at the Biophysics Research Laboratory:
- Designing, Developing and Optimizing Drug Delivery Systems for Spatially Controlled Delivery of various Anti-Cancer Drugs.
- Targeted Magnetic Nanoparticles for Different Delivery and Controlled Release of Drugs.
- Understanding the Interaction Between multi-Functional Nano-Materials (Graphene Oxide, Gold Nanoparticles and Carbon Nanotubes (CNT’s)) with Biological Systems to Improve Specific Drug Loading and Release.
- Advanced spectroscopic Analysis of the Interaction Between Anti-Cancer Drugs Targeted Liposomes & Blood Proteins.
- Biophysics of Lipid Membranes and Lipid- Amyloid Protein Interactions in relation to Alzheimer’s Disease.
- Molecular Study of Folic Acid Delivery by Pregnant’s Serum Proteins in First and Third Trimester of Pregnancy
- Study of the interactions between different proteins (such as transthyretin, beta amyloid, Bovine Serum Albumin and Human serum albumin) and a variety of drugs and ligands such as pentobarbital, propofol, arginine, Procaine, Dopamine cholesterols and vitamins.
- Application of Lipid Films in Biomedical Nanotechnology Field.
- Saponin-Cholesterol Interactions with Model Membrane Systems.